News Summary
Dr. Salvador Plasencia has pleaded guilty to four counts of distribution of ketamine, which contributed to actor Matthew Perry’s accidental overdose death. This plea highlights the ongoing issues of illegal drug distribution and medical ethics in the rapidly expanding at-home ketamine industry. Plasencia faces a possible maximum sentence of 40 years in prison, after admitting to his role in providing the drug to Perry. The case has raised alarm over unregulated ketamine use and the responsibility of medical professionals in safeguarding patient health.
Los Angeles, California —
In a significant legal development, Dr. Salvador Plasencia pleaded guilty to four counts of distribution of ketamine on July 23, 2025, in connection with the death of actor Matthew Perry, who died from an overdose of the drug last year. The plea marks a pivotal moment in a case that has shed light on illegal drug distribution and medical ethics within the rapidly growing at-home ketamine industry.
Details of the Guilty Plea and Sentencing Outlook
During a court hearing held on July 23, 2025, Dr. Plasencia admitted to his involvement in providing ketamine to Perry, acknowledging his role in the circumstances leading to the actor’s death. In response, Plasencia’s legal counsel described him as “profoundly remorseful” and noted he is accepting responsibility for his actions. As part of his plea agreement, Plasencia is voluntarily surrendering his medical license, a step indicating acknowledgment of his failure to safeguard Perry’s health.
He remains out on bond until his sentencing scheduled for December 3, 2025. Prosecutors have indicated that Plasencia faces a potential maximum sentence of 40 years in prison—10 years for each count of distribution—and may also be subjected to fines up to $2 million. The case underscores the serious legal repercussions associated with drug distribution and violations of medical ethics.
The Circumstances of Matthew Perry’s Death
Matthew Perry passed away on October 28, 2023, in his Los Angeles residence. The official cause of death was attributed to the acute effects of ketamine combined with drowning, with authorities ruling the death as accidental. An investigation launched by the Los Angeles Police Department months after Perry’s passing explored the circumstances surrounding his overdose. The investigation uncovered a network of illegal drug suppliers and doctors involved in the distribution of ketamine to Perry despite his ongoing therapy for depression and anxiety.
Legal Actions and Other Accused Parties
In August 2024, authorities charged five individuals in connection with Perry’s death, including Dr. Salvador Plasencia. Among those charged, Kenneth Iwamasa, Perry’s live-in assistant, pleaded guilty to conspiracy to distribute ketamine causing death. Erik Fleming, another supplier, admitted to providing the ketamine that led to Perry’s overdose, also pleading guilty to multiple counts. Additionally, Dr. Mark Chavez has pleaded guilty to drug distribution charges.
A key figure in the case is Jasveen Sangha, known publicly as the “Ketamine Queen,” who has pleaded not guilty and is scheduled for trial in August. Investigations revealed that Plasencia had received an underground network of drug sellers and suppliers responsible for orchestrating the distribution chain that facilitated Perry’s death.
Illicit Ketamine Use and Medical Ethics Violations
Evidence suggests that Matthew Perry was seeking out ketamine illegally, despite being under medical treatment for mental health disorders. Text messages discovered during the investigation indicated that Plasencia and other suppliers mocked Perry’s willingness to pay high sums—up to $55,000—for ketamine in the month before his death.
Furthermore, prosecutors highlighted that Plasencia had instructed Iwamasa on how to administer ketamine to Perry, despite Iwamasa having no medical training. This breach of medical procedure and ethics underscores the dangerous scale of unregulated drug sales intertwined with healthcare professionals.
Implications for the At-Home Ketamine Industry
The case has drawn significant attention from federal prosecutors, who see it as a serious violation of ethical standards and medical regulations. The actions taken against Plasencia and others are viewed as a warning to both medical providers and illegal drug dealers about the severe legal consequences of such conduct. Experts believe the case will catalyze stricter oversight and regulatory measures within the at-home ketamine treatment market.
In recent years, the popularity of outpatient ketamine clinics and at-home treatments has burgeoned, but this case highlights the potential dangers associated with unregulated distribution channels, especially where medical oversight is inadequate or absent.
Background and Broader Context
Matthew Perry, best known for his role on the television show “Friends,” became publicly known for his struggles with depression and substance abuse. Despite ongoing psychiatric therapy, Perry reportedly turned to illegal methods for accessing ketamine, a drug increasingly used both illicitly and in authorized medical settings for depression treatment. The investigation revealed that Perry’s use of ketamine involved purchases from underground networks, facilitated by individuals like Plasencia.
The case’s significance extends beyond Perry’s death, prompting discussions on the regulation of ketamine distribution and the responsibilities of medical professionals in overseeing drug treatment. Authorities hope that legal actions against Plasencia and others will serve as a deterrent and lead to safer, more regulated access to ketamine therapy.
Conclusion
As the legal proceedings continue, the case underscores a stark warning about the dangers of unregulated drug distribution and unethical medical conduct. The next court sessions will determine the precise sentencing, but the case already marks a critical moment in addressing the vulnerabilities within the at-home ketamine industry and the broader public health concerns associated with illegal drug use and medical law violations.
Deeper Dive: News & Info About This Topic
HERE Resources
Dr. Salvador Plasencia Pleads Guilty in Ketamine Case
Additional Resources
- The Guardian
- Wikipedia: Ketamine
- CNN
- Google Search: Matthew Perry death ketamine
- ABC News
- Google Scholar: Ketamine Ethics
- Al Jazeera
- Encyclopedia Britannica: Medicine
- Boston.com
- Google News: Matthew Perry ketamine

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RALEIGH STAFF WRITER The RALEIGH STAFF WRITER represents the experienced team at HERERaleigh.com, your go-to source for actionable local news and information in Raleigh, Wake County, and beyond. Specializing in "news you can use," we cover essential topics like product reviews for personal and business needs, local business directories, politics, real estate trends, neighborhood insights, and state news affecting the area—with deep expertise drawn from years of dedicated reporting and strong community input, including local press releases and business updates. We deliver top reporting on high-value events such as the North Carolina State Fair, Raleigh Arts Festival, and the Hopscotch Music Festival. Our coverage extends to key organizations like the Greater Raleigh Chamber of Commerce and Visit Raleigh, plus leading businesses in technology and education that power the local economy such as Red Hat and NC State University. As part of the broader HERE network, including HEREAsheville.com, HERECharlotte.com, HEREGreensboro.com, and HEREOBX.com, we provide comprehensive, credible insights into North Carolina's dynamic landscape.